Publications

Cherrak Y, Filella-Merce I, Schmidt V, Byrne D, Sgoluppi V, Chaiaheloudjou R, Betzi S, Morelli X, Nilges M, Pellarin R, Durand E. Inhibiting Type VI Secretion System Activity with a Biomimetic Peptide Designed To Target the Baseplate Wedge Complex. mBio. 2021 Aug 31;12(4):e0134821. doi: 10.1128/mBio.01348-21. Epub 2021 Aug 10. PMID: 34372705 .

Flaugnatti N, Rapisarda C, Rey M, Beauvois SG, Nguyen VA, Canaan S, Durand E, Chamot‐Rooke J, Cascales E, Fronzes R & Journet L. Structural basis for loading and inhibition of a bacterial T6SS phospholipase effector by the VgrG spike. EMBO Journal (2020), Volume 39, Issue 11 https://doi.org/10.15252/embj.2019104129

Crepin A, Kučerová Z, Kosta A, Durand E, Caffarri S. Isolation and characterization of a large Photosystem I-Light Harvesting complex II supercomplex with an additional Lhca1-a4 dimer in Arabidopsis. Plant J. 2019 Dec 6. doi: 10.1111/tpj.14634. [Epub ahead of print] PMID: 31811681

Cherrak Y, Flaugnatti N, Durand E, Journet L, Cascales E. Structure and Activity of the Type VI Secretion System. Microbiol Spectr. 2019 Jul;7(4). doi: 10.1128/microbiolspec.PSIB-0031-2019. Review. PMID: 31298206

Chiara Rapisarda, Yassine Cherrak, Romain Kooger, Victoria Schmidt, Riccardo Pellarin, Laureen Logger, Eric Cascales, Martin Pilhofer, Eric Durand*, Remi Fronzes* (co-corresponding author*). In situ and high-resolution Cryo-EM structure of the Type VI secretion membrane complex. EMBO Journal. 2019 Mar 15. pii: e100886. doi: 10.15252/embj.2018100886.  PMID: 30877094

Cherrak Y, Rapisarda C, Pellarin R, Bouvier G, Bardiaux B, Allain F, Malosse C, Rey M, Chamot-Rooke J, Cascales E, Fronzes R, Durand E. Biogenesis and structure of a type VI secretion baseplate. Nat Microbiol. 2018 Dec;3(12):1404-1416. doi: 10.1038/s41564-018-0260-1. Epub 2018 Oct 15. PMID: 30323254

Zoued A, Duneau JP, Durand E, España AP, Journet L, Guerlesquin F, Cascales E. Tryptophan-mediated Dimerization of the TssL Transmembrane Anchor Is Required for Type VI Secretion System Activity. J Mol Biol. 2018 Mar 30;430(7):987-1003. doi: 10.1016/j.jmb.2018.02.008. Epub 2018 Feb 17. PMID: 29458124

Nguyen VS, Douzi B, Durand E, Roussel A, Cascales E, Cambillau C. Towards a complete structural deciphering of Type VI secretion system. Curr Opin Struct Biol. 2018 Apr;49:77-84. doi: 10.1016/j.sbi.2018.01.007. Epub 2018 Feb 2. PMID: 29414515

Douzi B, Trinh NTT, Michel-Souzy S, Desmyter A, Ball G, Barbier P, Kosta A, Durand E, Forest KT, Cambillau C, Roussel A, Voulhoux R. Unraveling the Self-Assembly of the Pseudomonas aeruginosa XcpQ Secretin Periplasmic Domain Provides New Molecular Insights into Type II Secretion System Secreton Architecture and Dynamics. mBio. 2017 Oct 17;8(5):e01185-17. doi: 10.1128/mBio.01185-17. PMID: 29042493

Zoued A, Durand E, Santin YG, Journet L, Roussel A, Cambillau C, Cascales E. TssA: The cap protein of the Type VI secretion system tail. Bioessays. 2017 Oct;39(10). doi: 10.1002/bies.201600262. Epub 2017 Aug 17. PMID: 28817192

Durand E, Lloubes R. Large Complexes: Cloning Strategy, Production, and Purification. Methods Mol Biol. 2017;1615:299-309. doi: 10.1007/978-1-4939-7033-9_24.